Project area C deals with the formation and transport of vesicles. In an exemplary way, vesicular transport in eukaryotic cells is underlain by a modular organisation. Protein complexes such as vesicle coats or tethers must assemble and disassemble with cargo and also other functional elements for the very purpose of transport. Although each transport step, e. g. between the endoplasmic reticulum and the Golgi or between the Golgi and the plasma membrane, depends on its own specific protein repertoire, one also observes the shared usage of elements in different modules or submodules.

C3: Specific recruitment of viral components and assembly of enveloped viruses

C5: Modules involved in endosomal/lysosomal ion homeostasis and function

C7: Structural and functional analysis of the dynamin module

C8: Functional organization and dynamics of PI4-kinase-based modules for protein sorting at endosomal membranes

C9: Sub-modules in synaptic vesicle membrane targeting, fusion and endocytosis