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Second Funding Period (2011 - 2014)

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Second Funding Period (2011 - 2014)

Subproject Topic Project Investigators
A3 Structure and Dynamics of Eukaryotic 80S Ribosomes during the Elongation Phase of Protein Synthesis Prof. Dr. Christian M. T. Spahn
A4 The sub-module for spliceosome catalytic activation and disassembly Prof. Dr. Markus Wahl
A5 Dynamics of sub-modular and molecular interactions in translational elongation Prof. Dr. Zoya Ignatova
B1 Self-assembly and cellular function of modular p97/VCP protein complexes Prof. Dr. Erich Wanker
B3 Regulation of proteasome modules Dr. Elke Beate Krüger, Prof. Dr. Peter-M. Kloetzel
B5 Substrate recognition by the HRD-ubiquitin ligase Prof. Dr. Thomas Sommer, Dr. Ernst Jarosch
B6 Permanent vs. transient interactions between biopolymers in modular function PD Dr. Peter Hildebrand
B7 The interactions of small heat shock proteins with their substrates investigated by MAS NMR and dynamic nuclear polarization Prof. Dr. Hartmut Oschkinat, Dr. Barth-Jan van Rossum
C1 Modular organisation of vesicle tethering to membranes: Analysis of structural features and regulation by protein palmitoylation Prof. Dr. Udo Heinemann, PD Dr. Michael Veit
C3 Specific recruitment of viral components and assembly of enveloped viruses Prof. Dr. Andreas Herrmann, PD Dr. Michael Veit
C5 Modules involved in endosomal/lysosomal ion homeostasis and function Prof. Dr. Dr. Thomas J. Jentsch
C7 Assembly and mechano-chemical function of the dynamin submodule Prof. Dr. Oliver Daumke
C8 Functional organization and dynamics of PI4-kinase-based modules for protein sorting at endosomal membranes Prof. Dr. Volker Haucke, Prof. Dr. Michael Krauss
D1 The regeneration module in photoreceptor cells Dr. Martin Heck, Prof. Dr. Klaus-Peter Hofmann
D2 The negative feedback module of the circadian oscillator: dynamics of protein interaction and stability Prof. Dr. Achim Kramer
D3 The modular function of the g-secretase in the generation of intermediate Aß species Prof. Dr. Gerhard Multhaup
D7 From molecular patterns to transport in specific geometries: Spatial effects on the function of the phototransduction module Dr. Frank Noé
D8 Spatial modeling of gradient sensing exemplified for the yeast pheromone response Prof. Dr. Dr. H.c. Edda Klipp
Z1 Molecular electron microscopy and electron tomography Dr. Thorsten Mielke, Prof. Dr. Christian M. T. Spahn