Second Funding Period (2011 - 2014)

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Second Funding Period (2011 - 2014)

Subproject

Topic

Project Investigators

A3

Structure and Dynamics of Eukaryotic 80S Ribosomes during the Elongation Phase of Protein Synthesis

Prof. Dr. Christian M. T. Spahn

A4

The sub-module for spliceosome catalytic activation and disassembly

Prof. Dr. Markus Wahl

A5

Dynamics of sub-modular and molecular interactions in translational elongation

Prof. Dr. Zoya Ignatova

B1

Self-assembly and cellular function of modular p97/VCP protein complexes

Prof. Dr. Erich Wanker

B3

Regulation of proteasome modules

Dr. Elke Beate Krüger, Prof. Dr. Peter-M. Kloetzel

B5

Substrate recognition by the HRD-ubiquitin ligase

Prof. Dr. Thomas Sommer, Dr. Ernst Jarosch

B6

Permanent vs. transient interactions between biopolymers in modular function

PD Dr. Peter Hildebrand

B7

The interactions of small heat shock proteins with their substrates investigated by MAS NMR and dynamic nuclear polarization

Prof. Dr. Hartmut Oschkinat, Dr. Barth-Jan van Rossum

C1

Modular organisation of vesicle tethering to membranes: Analysis of structural features and regulation by protein palmitoylation

Prof. Dr. Udo Heinemann, PD Dr. Michael Veit

C3

Specific recruitment of viral components and assembly of enveloped viruses

Prof. Dr. Andreas Herrmann, PD Dr. Michael Veit

C5

Modules involved in endosomal/lysosomal ion homeostasis and function

Prof. Dr. Dr. Thomas J. Jentsch

C7

Assembly and mechano-chemical function of the dynamin submodule

Prof. Dr. Oliver Daumke

C8

Functional organization and dynamics of PI4-kinase-based modules for protein sorting at endosomal membranes

Prof. Dr. Volker Haucke, Prof. Dr. Michael Krauss

D1

The regeneration module in photoreceptor cells

Dr. Martin Heck, Prof. Dr. Klaus-Peter Hofmann

D2

The negative feedback module of the circadian oscillator: dynamics of protein interaction and stability

Prof. Dr. Achim Kramer

D3

The modular function of the g-secretase in the generation of intermediate Aß species

Prof. Dr. Gerhard Multhaup

D7

From molecular patterns to transport in specific geometries: Spatial effects on the function of the phototransduction module

Dr. Frank Noé

D8

Spatial modeling of gradient sensing exemplified for the yeast pheromone response

Prof. Dr. Dr. H.c. Edda Klipp

Z1

Molecular electron microscopy and electron tomography

Dr. Thorsten Mielke, Prof. Dr. Christian M. T. Spahn