First Funding Period (2007 - 2010)

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First Funding Period (2007 - 2010)

Subproject

Topic

Project Investigators

A1

Dynamics of genome duplication machines

Dr. M. Cristina Cardoso

A3

Structure and Dynamics of Eukaryotic 80S Ribosomes during the Elongation Phase of Protein Synthesis

Prof. Dr. Christian M. T. Spahn

A4

The sub-module for spliceosome catalytic activation and disassembly

Prof. Dr. Markus Wahl

B1

Functional analyses of VCP/p97 containing protein complexes involved in protein folding and degradation

Dr. Annett Böddrich, Prof. Dr. Erich Wanker

B2

Structural characterization of chaperone modulated protein aggregation in S. cervisiae

Prof. Dr. Bernd Reif

B3

The modular process of proteasome assembly

Dr. Elke Beate Krüger, Prof. Dr. Peter-M. Kloetzel

B4

Structural and functional characterization of complex protein modules involved in regulation of proteasomal activity

Prof. Dr. Michael Groll

C1

Modular organisation of vesicle tethering to membranes: Analysis of structural features and regulation by protein palmitoylation

Prof. Dr. Udo Heinemann

C3

Specific recruitment of viral components and assembly of enveloped viruses

Prof. Dr. Andreas Herrmann, PD Dr. Michael Veit

C4

Modular assembly, plasma membrane targeting and regulation of KCNQ (Kv7) K+ channels

Prof. Dr. Thomas Friedrich

C5

Protein modules involved in vesicular acidification and trafficking: Focus on ClC-6

Prof. Dr. Dr. Thomas J. Jentsch

C6

The Arf GTPase module in vesicle formation: coordination of coat recruitment and membrane bending with ArfGAP activity

Volker Haucke Ph.D.

C7

Assembly and integration of an EHD2 submodule involved in membrane remodelling

Prof. Dr. Oliver Daumke

D1

The regeneration module in photoreceptor cells

Dr. Martin Heck, Prof. Dr. Klaus-Peter Hofmann

D2

The negative feedback module of the mammalian circadian oscillator: functional impact of phosphorylation

Prof. Dr. Achim Kramer

D3

Characterization of the enzyme/substrate submodule and molecular recognition in the g-secretase complex

Prof. Dr. Robert Bittl, Prof. Dr. Gerd Multhaup

D4

Regulatory phosphorylation of scaffolding proteins of the inside-out-signaling complex

Dr. Christian Freund

D5

The role of rhodopsin opligomers in the amplifier submodule of retinal rods

PD Dr. Oliver P. Ernst, Prof. Dr. Klaus-Peter Hofmann

Z1

Molecular electron microscopy and electron tomography

Dr. Thorsten Mielke, Prof. Dr. Christian M. T. Spahn